HIV-1 Integrase Inhibitor 7
CAS No. 1235379-91-5
HIV-1 Integrase Inhibitor 7 ( —— )
Catalog No. M10942 CAS No. 1235379-91-5
HIV-1 Integrase Inhibitor 7 is an allosteric HIV-1 integrase inhibitor that inhibits the LEDGF/p75-integrase interaction.
Purity : >98% (HPLC)
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Biological Information
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Product NameHIV-1 Integrase Inhibitor 7
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NoteResearch use only, not for human use.
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Brief DescriptionHIV-1 Integrase Inhibitor 7 is an allosteric HIV-1 integrase inhibitor that inhibits the LEDGF/p75-integrase interaction.
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DescriptionHIV-1 Integrase Inhibitor 7 is an allosteric HIV-1 integrase inhibitor that inhibits the LEDGF/p75-integrase interaction with IC50 of 0.58 uM, antiviral activity EC50 of 0.76 uM.
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Synonyms——
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PathwayMicrobiology/Virology
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TargetHIV
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RecptorHIV
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Research Area——
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Indication——
Chemical Information
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CAS Number1235379-91-5
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Formula Weight353.48
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Molecular FormulaC21H23NO2S
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name2-(2,6-dimethyl-4-(p-tolyl)thieno[2,3-b]pyridin-5-yl)pentanoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Helichrysetin
Helichrysetin has mild anti-HIV-1 PR activity. Helichrysetin has great potentials for development as an anticancer agent, it has cytotoxic effect on four selected cancer cell lines, A549, MCF-7, Ca Ski, and HT-29.Searching for anti-HIV-1 protease (PR) inhibitors of Thai medicinal plants led to the isolation of a new cyclohexenyl chalcone named panduratin C and chalcone derivatives (2-6) from the methanol extract of Boesenbergia pandurata rhizomes.
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Ditiocarb sodium
Ditiocarb sodium (Sodium diethyldithiocarbamate) is an accelerator of the rate of copper cementation. Sodium diethyldithiocarbamate reduces the incidence of HIV infection.
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Peptide T TFA
Peptide T (TFA) is an octapeptide from the V2 region of HIV-1 gp120. Peptide T is a ligand for the CD4 receptor and prevents binding of HIV to the CD4 receptor.